DNA Diet Test

The DNA Diet test is suitable for anyone who wants to manage their weight and imrpove their overall health

• Provides strategies for weight management based on genetic make-up
• Provides motivation to individuals with a goal to lose weight
• Provides an understanding of why previous weight management programmes may have  been unsuccessful
• Provides insight to which diet type (i.e. Mediterranean style, low carbohydrate, low fat diet) may be most suited to an individual to manage weight, based on genotype 

Analytes measured:

Absorption and Metabolism

FABP2:  Influences fat absorption and metabolism.
PPARG: Involved in adipocyte differentiation. It is a transcription factor activated by fatty acids, and is also involved in the regulation of glucose and lipid metabolism.
ADRB2:  Involved in the mobilisation of fat from fat cells for energy, in response to catecholamines.
APOA5: Plays an important role in regulation of plasma triglycerides.

Fat Metabolism, Obesity and Satiety

APOA2: An abundant apolipoprotein in HDL. Plays a complex role in lipoprotein metabolism, insulin resistance, obesity and atherosclerosis susceptibility.

Regulation of Metabolism and Feeding Behaviour

MC4R: A strong obesity candidate gene, significantly associated with energy intake and expenditure.

Insulin Sensitivity and Regulation of Energy Intake

FTO: Involved in the regulation of arousal, appetite, temperature, autonomic function and  endocrine system.
TCF7L2: Regulates blood glucose homeostasis, influencing both insulin secretion and sensitivity.

Exercise Responsiveness

ADBR3: Involved in the regulation of lypolysis that influences metabolism.

Circadian Rhythms

CLOCK: An essential regulatory arm of the biological clock, involved in metabolic regulation.

Fat Storage

PLIN: Influences diet-induced obesity.

Inflammation

TNF-A: TNFa is a pro-inflammatory cytokine, secreted by both macrophages and adipocytes, which has been shown to alter whole body glucose homeostasis, and has been implicated in the development of obesity, obesity-related insulin resistance and dyslipidemia.

Carbohydrate Sensitivity and Eating Behaviour

TAS1R2: Believed to contribute to the inter-individual variation in sugar consumption.
SLC2A2 (GLUT2): Influences the first step in glucose induced insulin secretion, affecting both food intake  and regulation.
DRD2: Midbrain dopamine circuits may play an important role in both addiction and normal eating behaviour as they are involved in reward processing, particularly dopaminergic signalling via dopamine receptor 2 (DRD2).

Sample required:  Bloodspot (simple fingerprick test or buccal swab can be requested if required)

Average processing time: 18-21 days

Shipping: Test will be shipped to your address and then will be collected from your address and shipped directly to the laboratory

Privacy policy: The DNA and the original sample material are destroyed after 3 months, so that there are no names or other identifiers on the samples. The samples are analysed only for the SNPs that are included in the tests at DNALife, and no other research or analyses are performed without a separate permission from the patient. We do not give or sell the results to any third parties.